Dr. Ted Steele continues to communicate his heroic effort to compare the genomic sequences of distant Covid-19 infection locations. If the genes show little mutation it could prove the primary infection vector is from above, not handshaking. Unless the intrepid handshaker owned a Gulfstream 6 and managed to press the flesh in several areas of the globe almost simultaneously.
4/25/20 12:39 AM
Dear Chandra and colleagues;
A very large number of complete COVID-19 sequences for- at least ≥ 200 sequences – for period Mar 14 – Mar 22 , start of the rocket phase in NYC – have just been uploaded to NCBI Virus. Even the sample from the tiger in the Bronx Zoo.
So I will have to the analysis in bite-size stage, say 40 in a tranche, as the alignments will be far too big to do quickly on the screen( the scroll freezes at a certain size limit, about 40 on my computer. No information on where collected ( or any clinical patient data) in New York City , just “NY” as location label.
I will have to do this slowly and methodically.
I will reserve judgement- just tidying up China epidemic ( Dec-Jan) , and one of the USA West coast outbreaks CA+ Cruise Ship (Feb), So I have a load of work now- will focus on NY as my next job.
I was going OK on doing some sample NY COVID-19 alignments at NCBI Virus- but I think the site has crashed with user overload. I have established some very important general facts about the 192 NY sequences up loaded there ( Mar 14-Mar22)- but I cannot do an alignment not even a small one, say 25 sequences.
But I have manually harvested all the GenBank Accession Nos to the sequences, and taken screen shots of the key sites around the S Haplotype variant at p.8782, p28144 and this has given me already great insight into the data in NYC during the exponential rocket phase of the epidemic.
I have sent in an inquiry to NLM/NCBI Virus support. But I will reserve judgement until I can do alignments which I cannot do at the moment.